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EYLEA® (aflibercept) 8 mg

TREAT WITH A KNOWN MOLECULE AND SAFTY PROFILE

Safety profile

The reassurance of treating your patients with the tried-and-trusted aflibercept molecule

In PULSAR and PHOTON, EYLEA 8mg demonstrated a safety profile consistent with EYLEA 2mg from baseline through Week 96:*

PULSAR-PHOTON safety module

* EYLEA (aflibercept) 2mg was dosed at fixed Q8 intervals after 3 (nAMD) or 5 (DME) initial monthly injections.

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Safety Profile in Neovascular age-related macular degeneration (nAMD)

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Safety Profile in Diabetic macular oedema (DME)

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Dosing

Discover proactive dosing in nAMD and DME

Mechanism of Action (MoA)

Discover more about the MoA of EYLEA 8mg

Abbreviations

2Q8
, 2 mg every 8 weeks;
8Q12
, 8 mg every 12 weeks;
8Q16
, 8 mg every 16 weeks;
AE
, adverse event;
APTC
, Anti-Platelet Trialists’ Collaboration;
DME
, diabetic macular oedema;
IOI
, intraocular inflammation;
IOP
, intraocular pressure;
MoA
, mechanism of action;
nAMD
, neovascular (wet) age-related macular degeneration;
Q8
, every 8 weeks;
SAE
, serious adverse event;
SAF
, safety analysis set;
TEAE
, treatment-emergent adverse event.

PP-EYL_8mg-IE-0155-1   |   December 2025

    Referencesexpand_less
    • 1
      Korobelnik J-F. Intravitreal aflibercept 8 mg injection in patients with neovascular age-related macular degeneration: 48-week results from the Phase 3 PULSAR trial. Retina Society. 2–5 November 2022. Pasadena, USA. Oral presentation.
    • 2
      Do D. Aflibercept 8 mg for diabetic macular edema: 48-week results from the Phase 2/3 PHOTON trial. ARVO. 23–27 April 2023. Palo Alto, USA. Oral presentation.
    • 3
      Korobelnik J-F. Aflibercept 8 mg in patients with neovascular age-related macular degeneration: Phase 3 PULSAR trial 96-week results. AAO. 3–6 November 2023. San Francisco, USA. Oral presentation.
    • 4
      Wykoff CC. Aflibercept 8 mg for diabetic macular edema: 96-week results from the Phase 2/3 PHOTON trial. EURETINA. 5–8 October 2023. Amsterdam, The Netherlands. Oral presentation.
    • 5
      EYLEA® 114.3 mg/mL Summary of Product Characteristics.
    • 6
      Lanzetta P, et al. Intravitreal aflibercept 8 mg injection in patients with neovascular age-related macular degeneration: 60-week and 96-week results from the Phase 3 PULSAR trial. EURETINA. 5–8 October 2023. Amsterdam, The Netherlands. Oral presentation.