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Kyleena® (19.5mg Intrauterine Delivery System Levonorgestrel)

Mechanism of Action

Model Image

Kyleena® : has a different mechanism of action to the pill

  • Kyleena® offers a localised, oestrogen-free mechanism of action with a low dose of Levonorgestrel.
  • The endogenous hormone production is unaffected and ovarian function remains normal in most women.
Natural Menstrual Cycles

Natural Menstrual Cycles

Natural Menstrual Cycle
Menstrual Cycle with LNG-IUS & Cu IUD[

Menstrual Cycle with LNG-IUS & Cu IUD

IUS Icon in Circle
Menstrual Cycle with OCs such as POPs

Menstrual Cycle with OCs such as POPs

Pills in Purple circle Icon
Legends

Patient Case Studies:

Case Study - Anxious about hormones
Jade: Anxious about hormones
23-year-old non-smoker anxious about hormones and wants a non-hormonal contraceptive option.
PP-KYL-IE-0259-1, January 2026
Case study 2 - The tricky fit
Mandy: The tricky fit
This patient has been referred to you from a colleague "unable to pass an uterine sound".
PP-KYL-IE-0260-1, January 2026
Case study 3 - The forgetful pill taker
Sonila: The forgetful pill taker
19-year-old university student struggling to remember to take her pill every day but is concerned about an unplanned pregnancy.
PP-KYL-IE-0261-1, January 2026

PP-KYL-IE-0253-1   |   January 2026

    • 1
      Kyleena® 19.5 mg intrauterine delivery system (levonorgestrel): Summary of Product Characteristics.
    • 2
      Alvergne and Lummaa. Trends in Ecology and Evolution, 2010;25(3):171–179.
    • 3
      Apter D, et al. Fertil Steril, 2014;101:1656–1662.
    • 4
      ParaGuard® Prescribing Information, Cooper Surgical, 2018.